You may also like the most reading. In your opinion, Dr. Muhammad Al-Mahrouji writes for "Al-Shorouq": Metokondrea Bird in a garden.. A vital secret, a shining star beyond 90.
(To the sunrise and its dear days and the memory of the man who was in its board)
After we received at the entrance surrounded by flowers, he invited us to his ether corner in the inner garden. We were ten who specialized in calling for lunch, most of them were his students and close friends who knew the place well, while this was the first time he supervised his invitation. We distributed us to the sofas and comfortable seats under a shaded sewage with plants, and it was not mediated, but his friendly magic, and radish at the same time made him the center of the plural in this place that is historical in some way. He was a global figure on merit, and a core Egyptian, which was smoothly manifested in this session, as he was talking to the world through calls from four parts of the earth, and at the same time interferes with us the ten with a clear vigilance and loved familiarity. After about an hour and a half, he received a reference from his wife, Mrs. Hadayte, as if she was dangerous, and he got up, calling us to lunch. We crossed the hallway of the house very elegant and deeply familiar at the same time, and we found in the "terrace" overlooking the front garden several round tables that we distributed without arrangement. He did not sit. And because, as usual, I was "I was not" in my comfort in eating on tables that I was called outside the unilateral and intimacy of my family, I went to my mind and my feet, and I allowed myself - when I discovered that this is acceptable - to roam here and there through the open doors on the terrace, so I met books with every step, In Arabic, English and French, Shi was reading in more than one book at the same time, reading all the time, and in all places.
A phenomenon calling for a salt, Professor Heikal, that I do not eat as I should, so he took me to the buffet, picked up a dish and started to fear me what incites me to taste and turn to him, I dealt with the dish, thanking him for his affection, but I did not sit, but I carried the dish walking, "savvy" what he chose for me and he was Indeed, while most of my preoccupation was directed to the meditation of this man, this phenomenon. There is no doubt that I love him, my love for every high talent, whatever agreement or difference with its owner. It was a real talented temple, I say it with confidence in a reading reader in the depths of reading more than half a century. Heikal is one of the masters of Arabic writing, the one that literary criticism in our country was generalized, which belongs to the type that built a bridge between the press and literature, entitled "Faction Truth"), and not (FCTION), the one that came out of its womb " In -depth investigation and “journalistic story”, and I claim that Heikal was one of the masters of this type of literature of the press, not only in our Arab world, but in the world. Professor Heikal was talented in many spectra of activities, its axis and mirror, but there is a spectrum that did not He has the obligatory stoppage, as it requires a kind of medical insight, and reflect on what the prisons and the "aging" mean, and I think I am excused for this sedition and this imprisonment, not only because I and many who loved us have reached the age of this scope, but because I lived the prisons of aging with many close to My heart, which inherited me with a resident obsession, is not that I suffer from these prisons, as this is appreciated and able to be patient, satisfied, and soothing medicine (if found), but that those who loved them and love me will measured what can happen to them from the burdens of grave, which are shattered by bodies and souls who are loved by a lover or near It is struck by aging diseases, no. For this, it was normal for me to fascinate the vitality of Haykal on that day while he was in the ninety "terrace", and he remained on this vitality - especially - until his departure at the age And light shoes, the light of all colors, and I contemplated it while moving with vitality between his guests, and in the presence of my mind sends and receives the conversations that take place at lunch, with the grace of the Bing Pong Passive player and the accurate correction. guy! A young man in ninety! Issal's storm of life. How did he nurture him? I knew something that carries me to the first answer, then made sure what I knew about the conversation of the virtuous lady, Hadit Taymour on that day, she told her laughing how she was initially resisted moving from her home in Cairo and living in this house in the village The miracle of the professor is that there is no objection, but with dinner! I realized that what was rumored that Heikal was excluded from his dinner meal was true, and surprisingly, he started this while he was forty! A very early start I made it to follow the "Calories Restriction" system, and that was the beginning of my sacrifice in trying to answer a big question in medicine, as it is in the fate of human life.
Miracle of 1 of a thousand millimeters since the twenties of the twentieth century The "calorie restriction" system has been proposed as a quality effect on health with longevity. It has been found that the mice that have been blocked with balanced meals are 40% lower than usual, their suffering of aging diseases has decreased with an increase in their ages by half compared to others who were well fed! After that, research on the calorie restriction system and its positive impact on health with aging, especially in the past twenty years, then manifested the role of "mitochondria" as a key player in this regard, which puts it in the focus of attention as a vital miracle in our bodies, despite its endowment. Metochondria, and its individual "mitochondion", and the "bumps" and its unique "are" adapted ", are organs that occupy an average of one micron, which is part of a thousand millimeters, and is found in the cytoplasm of all the cells of the human body, with the exception of red blood blood cells, while their numbers differ in Each type of cell. As it is mainly the power generator who provides the cell with 90% of its needs, it is dense in the cells that need a lot of energy, such as heart cells, retina, muscles, and liver. And the last - for example - because it performs hundreds of vital processes, each of its cells includes between 1000 and 2000 mitochondria, occupying the fifth of the cell. However, in 1948, the biochemistry, Albert Lennger, and his colleague, "Oxidative phosphorylation", which generates most energy in real core cells, of carbohydrates, fatty acids and proteins (to a lesser degree), in the presence of the presence The oxygen, and the energy generated in this way takes a chemical form is "ATP" adenosine, and this process consists of a series of picturesque reactions as if it was an impressive rhythm art show, the energy required to complete each reaction is obtained by moving electrons between a protein matrix, extracted from one and added to The following, then the latter loses it to go beyond, and in each electron leap, a small amount of energy is generated used to complete the reaction, and so on until the last reaction to combine phosphate with Adenosin ADP dual phosphate to form the peak of the width, Edinosin three phosphate "ATP".
The composition of the mitochondria, as in the super art, there is a second peak after the first, and here is the launch of the major energy by adding a water part to the ATP part and the latter's return to the ADP again, and again this great offer continues, to generate sustainable energy, very generous, and extremely economical at the time Himself, the oxidative phosphorus produces 34 ATP parts of one glucose molecule. However, exactly - inside the mitochondria - this miracle occurs? And how? This question did not start answering it until three years after the discovery of the oxidative phosphate production of the production of three phosphate, with the development of the electronic microscope, pictures of the mitochondria minutes revealed its amazing composition simplicity and genius, from two membranes, and they make an integrated vital chemical industrial complex. A thin and permeable outer membrane, its protein gaps allows the passage of the cell cytoplasm and requires the total work of mitochondria. And an internal domestic membrane is permitted only with the passage of what it selects to complete the energy production reactions, and it is thick, zigzag, which increases its surface area to accommodate the series of these interactions, and that every nakedness in it makes a hump that separates each area and another so that no interaction is confused. A genius production line for energy, vital, and neighborhood, but .. it occurs on the sidelines of this tremendous achievement, the appearance of a controversial side producer, is the interactive oxygen, which opens to the heart of the debate in the dilemma For the consequences in the cell, and then in the entirety of the body, its role in generating energy remains the largest, and the axis around which all its effects revolve around our existence, from small to the oldest, and from life to death. Two paths seem to be opposed, but they are from one source, its main title "oxidative phosphory", and its sub -title "interactive oxygen", and the last is only oxygenate compounds, for example, the roots (or free radicals) of oxygen ions, which are excessive or chemical activity. Laming it in addition from the single electrons, so it causes harmful oxidation of the components of mitochondria - especially its proteins - if the antioxidant capabilities in the mitochondria exceeded. But if there is a balance, the interactive oxygen acts as an alarm bell that alerts the mitochondria to slow the pace of its rush to generate exaggerated energy, otherwise .. the reins escape by leaving huge amounts of interactive oxygen, so that the oxidation begins to redeem it in an anti -destructive series, it leaves deformed proteins, And the inability to produce sufficiency of energy, so the death of mitochondria begins without regeneration (by bilateral division) and then the death of cells. And aging is only the death of cells that are not sufficient compensation for them. As for aging diseases, they are added suffering. In particular, Alan Wright and his colleagues from Edinburgh University have proven that aging diseases are related to the excessive increase of the rate of free radical leakage through mitochondria over time. If this leakage is rapid, Degenerative Diseases appear, which are diseases where the function or structure is decreased in the tissues or affected organs over time, such as osteoporosis, Great Arthritis and Alzheimer's disease. If the leakage is slow, these diseases are postponed, and it may disappear. But when the mitochondria groups begin to wear and decade the cells, and the leakage of the roots or free radicals turns into a sweeping flood, these themselves are released to the whistle of the danger, and hundreds of genes are active in a confused attempt to restore healthy conditions, and excessive and inappropriate responses occur from the immune system, which causes Chronic inflammatory diseases, and these represent most of the aging diseases, from rheumatoid arthritis, arterial stiffness, heart disease, and others. Is there a glimmer of hope for old age without these degeneration and these infections, or even with a few uncomfortable ones?
Cleaning the place to receive the new. There is a scientific opinion that does not like the use of manufactured antioxidants; Because it remains strange substances that the body does not recognize, and it is pronounced without vilification. Also, there are those who see the lack of logic in the transmission of anti -oxidants in order to eliminate free radicals, so it is not possible to resist the burning of fires by disrupting the fire alarms, and here the calorie restriction system ascends as a preventive barrier against the increase in the rate of free radicals, without disrupting its vow and directed role For balance and restoration, and without the overthrow of its role very important in cleaning the square from the wreckage of the orbits and the damaged cells in favor of the multiplication of new mitochondria and renewable cells. The free radicals have the final word, if the estrangement and cell damage reach the degree of reference, it gives the starting signal by operating the "sample" or "programmed death" of the Apoptosis, and instead of degradation and turning into a benching of the bents as the cancer cells do when their final death, the steps of death goes on Programming to the autophage or self -devotion, so healthy cells absorb the remains of the cell that underwent the descent, so that these remains are inserted into a recycling process that supports the restoration and renewal of healthy cells. Thus, the calorie restriction system reduces the destroyed oxidation in the mitochondria, so that it maintains the state of balance in it, especially the protection stabilization that means the presence of healthy proteins, and allows the possibility of a long life without aging diseases, or with a little and unnecessary from them, which is reflected in the physical and psychological ability to resist The most dangerous surprises. Perhaps I do not broadcast secretly if I mentioned, in this regard, that when I saw him on that day at the house of Barqash, it was years before one of the few who defeated cancer, with a complete recovery.
Flying without wings in his Badi's book, "The Right of Life" issued in 2009, says a prominent biochemistry, and the wonderful scientific writer Nick Lin: "The calorie restriction system protects the body from aging diseases, at least if this begins early in life before the mitochondria is wore And there is nothing wrong with this in the middle of life. While doing this system for that, hundreds of genes that cause infections. These matters combined inhibit all of cancer and relaxed diseases and slow the rates of aging! I am amazing! It was up to me to use in the alienation of the way the human form is brought to the nearest being that resembles it, a method mentioned by Fakhr al -Din al -Razi in his book “The Pure”, and with it we infer from the known in the qualities of a being, on the unknown in those who are waving similar to him from humans. I could only find a bird's structure, fluttering here and there. For the surprise, when I was busy with the issue of the steadfastness of its vitality, the mental, especially despite the nineties that I saw in it and the ninety and the ninety that it reached, I was surprised that the human bird spoke to meet, with metaphor or metaphor, with a surprisingly real exception to birds in resisting aging diseases with the progress of their ages, and has proven research Many are also that this exception is also up to the vitality of the mitochondria, which has been proven to be not only in the cells of its bodies, but in its red blood cells, too! And for addition, the Spanish scientist "Gustav Barucha" performed a series of experiments that showed that the free radicals of birds were leaked by ten ten Fold it at its analogues of mammals when comparing it with the rate of consumption of oxygen, and this applies to the bats that resemble birds in the rate of leakage of free radicals from the limited mitochondria, and then it is likely that this paradox, or exception, relate to the action. It is true that a structure, as human beings, did not His red blood cells contain the mitochondria that were proven to exist in birds, and he did not have two wings to fly, but he was with his luxurious activity in writing, politics, thought, literature and passion for knowledge, shaving all the time, shaving du N stop, and a long -protected metochondria card with a calorie restriction system.
The age of time, and the healthy age remains that when I was collecting the information of this article, I noticed in many scientific papers a confusion between the concept of time and a healthy age, and "frankly", I was not convinced that a scientific study on a worm in a laboratory, even if the "graceful Lord" Caenorhabditis " Elegans, which was the research model in more than one study, can be interrupted by the possibility of prolonging or shortening human life, and my religious and spiritual convictions are not only what is speaking to me, and even scientific mental acts are likely to me; Because the issue of life is governed by interventions, intersections, surprises and endless possibilities, and it is impossible to control it combined. For this, what would have been going on to me here was the healthy age, which makes the human being a creative product on this land in his childhood and in his old age, and the calorie restriction system is only a means of reaching this goal, and the condition of Professor Heikal is an argument, but it is an argument that is not completed except by alerting that Following the calorie restriction system since the age of forty, it was only a single of a health deposits package that he saved in his youth and invested with an extension of life. A package between them: his early sleep and his early awakening, that is, harmony with the innate biological rhythm, and going out to practice outdoor walking in the morning, and memory exercises that re -awaken the inherent in the brain cells and their tree branches, he was always reviewing what he memorized from the hair, which is many, and not He misses a name or history that escapes from his memory while speaking or writing, and he is silent, and he drains his mind, no matter how long he is silent, until he holds the fugitive, and returns it to the lobby of memory, and which memory?!
The text is published in coordination with the "Forscience.com" magazine, which is the Egyptian Arab edition of Scientific America